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Allergies
  Seasonal or atopic. The eye is covered in a thin, transparent mucus membrane called the conjunctiva. The conjunctiva contains mast cells. When an allergan comes into contact with a mast cell, it literally explodes, releasing histamine. Histamine causes dilation of blood vessels and leakage of clear plasma from the capillaries. This causes the classic symptoms of redness, itching, and swelling.

   
   
Amblyopia
  Reduced visual acuity from a number of causes, but typically caused by early visual deprivation or high refractive error. Early diagnosis and treatment before the age of 5 years can lead to a successful outcome.

   
   
Best-Corrected Visual Acuity – BCVA
  The best Snellen acuity that can be obtained with correction. BCVA can be reduced following keratofractive surgeries and certain eye diseases such as keratoconus, macula degeneration, and optic nerve disease.

   
   
Binocular Vision
  The quality of vision obtained when both eyes are working together as a team. The advantages of binocular vision are better visual acuity and fine depth perception, called stereopsis.

   
   
CK
  Acronym for Conductive Keratoplasty, a non-incisional technique that involves the local heating and reshaping of corneal tissue to alter its refractive properties. Microwaves are applied very precisely to localized areas of the cornea in a circular pattern in order to shrink the collagen. This produces a steepening effect in the center. CK is approved only for the temporary reduction of farsightedness and for the temporary reduction of presbyopia in one eye only.

   
    CLE   Acronym for Clear Lens Extraction, the procedure whereby the natural lens of the eye is removed to correct high myopia. For example, if the power of the natural lens is approximately +12 diopters, then its removal will result in a one-to-one reduction in myopia of 12 diopters. However, when a CLE is performed in a young patient without presbyopia, the patient will lose the ability to see up close. The risks of a CLE are about the same as with any cataract surgery.

   
    Cataracts   Clouding of the crystalline lens due to age, trauma, certain eye diseases, drugs or radiation.

   
    Color Blindness   A congenital loss of the inability to discriminate between various colors or shades of colors. Can range from mild to severe, and is typically congenital. It is much more prevalent in males (X-linked).

   
    Contrast Sensitivity   The ability to perceive different spatial frequencies under conditions of varying contrast. An example of high contrast and high spatial frequency would be the 20/20 letter on a well-lit eye chart. An example of low contrast and low spatial frequency would be the ability to discern facial features under dim illumination. A loss of contrast sensitivity often occurs following keratorefractive surgeries such as LASIK, PRK, RK as well as certain eye diseases.

 
   
    Depth Perception   There are two kinds of depth perception: stereopsis and monocular. Stereopsis is the ability to perceive objects in 3D, or three dimensions. It can only occur when both eyes are working as a team. Other depth cues, such as shadow, relative size, relative motion, are called monocular cues because binocular vision is not required.

 
   
    Diabetic Retinopathy   Diabetes is a disease causing breakdown of the blood vessels and capillaries within the body. This can lead to small microaneurysms and hemorrhages in the retina, called background diabetic retinopathy. When severe oxygen deprivation occurs, new vessels are formed on the surface of the retina. This is called neovascularization. The new vessels are fragile and bleed. This is called proliferative diabetic retinopathy. At some point, intervention with laser treatment can prevent further neovascularization and hemorrhaging. Called “panretinal photocoagulation,” the aim is to destroy healthy retinal tissue to reduce oxygen demand.

 
   
    Double Vision   When the eyes do not line-up with the object of regard, double vision can be the result. This is called binocular diplopia. This is caused by the images falling on non-corresponding points of the two retinas. When a double image is perceived by one eye only, it is called monocular diplopia. Monocular diplopia can result from a distortion of the optical media, such as high astigmatism or corneal warpage, or a cataract.

 
   
    Dry Eyes   The tear film is a complex layer of lipid, aqueous, and mucus components, and many other biochemical constituents. Those substances are secreted by a number of different glands. The major lipid glands are the meibomian glands of the eyelids. The major aqueous-secreting gland is the lacrimal gland, located upper-outer quadrant of the orbit, and the various small accessory glands throughout the conjunctiva. Dry eye can result when any of the constituents is altered in terms of quantity or quality. Causes of dry eye are manifold, and include certain drugs such as antihistamines, Acutane, Retin-A, autoimmune diseases such as arthritis, or common hormonal changes. Dry eye is much more prevalent in women.

 
   
    Eyestrain   Also called “asthenopia.” Symptoms can range from mild discomfort to eye pain to headaches. This can be due to uncorrected refractive error or simply over-use of the eyes in stressful situations, such as prolonged reading or close work.

 
   
    Focusing Disorder   Accommodative insufficiency, accommodative infacility, or accommodative spasm are all disorders of the focusing system. The most common focusing disorder is simply due to the aging of the eye and is called presbyopia. Other forms are due to uncorrected refractive error, such as hyperopia(farsightedness), certain drugs such as atropine, antihistamines, and antidepressants, or genetic.

 
   
    GASH   An acronym used to describe the visual phenomena resulting from keratorefractive surgeries such as LASIK, PRK, and RK. It stands for Glare, Astigmatism, Starbursting, and Halos. The GASH symptoms are more intense, or likely to occur under conditions of low light when the pupils dilate. It is generally accepted that GASH symptoms are the result of a mismatch between the ablation zone or correction zone of the surgery and the pupil. RGP contact lenses are generally effective in resolving this problem. Additional surgeries are occasionally helpful

 
   
    Genetic Eye Diseases and Dystrophies   These can effect the cornea, the retina, or any part of the eye.


 
   
    Glaucoma   Not a single disease, but a family of diseases causing blindness as a result of pressure-induced atrophy of the optic nerve. Intra-ocular pressure is the primary risk factor for the development of glaucoma, but glaucoma can also occur under conditions of “normal” eye pressure. Certain other predisposing factors include family history and race. Glaucoma is treated with eye drops or surgery to lower the intraocular pressure. Loss of nerve function is measured by visual fields and by observation and measurement of the nerve.

   
    Hypertensive Retinopathy   Cardiovascular disease can lead to swelling and hemorrhages in the retina, as well as embolisms of arteries and veins within the retina. Early signs of hypertension are often visible within the eye as subtle changes in the appearance of the arteries and veins.

   
    ICL   Implantable Contact Lens. Also called a phakic IOL, or phakic intraocular lens, because it is placed in an eye without removing the natural lens. An ICL is used to correct high refractive errors such as nearsightedness and farsightedness that are beyond the safe range of other, non-invasive procedures such as LASIK or PRK. Complications of ICL implantation include glaucoma, secondary cataract, and infection.

   
    ICRS   Acronym for Implantable Corneal Ring Segments. The commercial name for ICRS is Intacs. Available in various curves and sizes, these acrylic ring segments are implanted within the cornea to reduce myopia by flattening the center of the cornea. Another use of Intacs is to improve the vision of patients with keratoconus. The effects of Intacs are somewhat limited to people with lower amounts of myopia. Also, the technique lacks the higher precision of other techniques such as LASIK and PRK. However, the effects are somewhat reversible, and there is no disturbance of corneal tissue within the optical zone.

   
    Infection  

Many microorganisms can infect the eye. The most common is the viral infection known as “pinkeye.” Caused by a number of common adenoviruses and spread through “fomites,” or droplets of saliva, “pinkeye” is usually of short duration and is self-limiting. Other viruses can cause more serious eye infections, such as EKC(epidemic kerato-conjunctivitis) and various herpes viruses such as herpes simplex or herpes zoster(shingles). These viruses can cause severe swelling, eye pain, and even loss of vision (seldom with EKC, more common with herpes).

Bacterial eye infections often accompany viral infections because of the breakdown in the eye’s local immune system. Others occur as primary infections. The more serious bacterial infections can cause an ulcer. Ulcerative eye infections are much more common with contact lens wear, especially overnight lens wear. These must be treated early and aggressively.

Still another type of infection is caused by parasites, such as demodex follicularum, or acanthamoeba keratitis. The former is a little mite that infects the eyelids, causing swelling and itching. The latter is a ubiquitous, but dangerous little amoeba that infects the cornea. It is a rare, but potentially blinding infection that also seems to have a predilection for contact lens wearers, especially when exposed to tap water, improperly disinfected swimming pools, hot tubs, or even contaminated soil. Early diagnosis and treatment is critical.


   
    Inflammation   Inflammation is the over-reaction of the body’s immune system, and can affect any part of the eye. It is characterized by invasion of the affected tissue by inflammatory cells such as lymphocytes, monocytes, and neutrophils. Inflammation is caused by infection, allergy, or autoimmune disease.

 
    Irregular Astigmatism   Astigmatism that cannot be completely resolved with sphero-cylindrical lenses is called irregular. Irregular astigmatism is sometimes induced by keratorefractive surgeries such as LASIK, CK, RK, and corneal transplants. A rigid contact lens will usually resolve this type of astigmatism.
 
   
    LASEK   Acronym for Laser Assisted Sub-Epithelial Keratomileusis, a surgical procedure designed to reduce or eliminate refractive errors such as nearsightedness, farsightedness, and astigmatism. The procedure involves removing the top layer of the cornea, called the epithelium, in one piece instead of the thicker flap as is done in LASIK. After the excimer laser is applied to remove the desired amount of corneal tissue, the layer of epithelium is replaced. LASEK is probably more similar to PRK, in which the epithelium is removed first and them allowed to re-grow over a period of two or three days. Currently, there do not seem to be any clear advantages of LASEK over conventional PRK. However, like PRK, flap complications are avoided.

   
    LASIK   Acronym for Laser Assisted In-Situ Keratomileusis, a surgical procedure designed to reduce or eliminate refractive errors such as nearsightedness, farsightedness, and astigmatism. The procedure is performed by first making a thin flap of corneal tissue, folding it out of the way, then altering the shape of the cornea by subtracting tissue using an excimer laser. The flap is then replaced over the treated area. This method results in more rapid visual recovery and less discomfort than other refractive surgery methods.

   
    Learning Related Vision Disorder   A vision condition can result in retardation of reading skills. Reading involves a complex series of eye movements. Eyestrain from uncorrected refractive error or a binocular vision disorder can lead to slow and inefficient visual processing. Visual conditions commonly involved in visual learning disorders are uncorrected farsightedness and convergence insufficiency.

   
    Macular Degeneration   The macula is the part of the retina containing the greatest density of photoreceptors called cones. Loss of macular function results in loss of visual acuity in mild forms to a complete loss of central vision, or blindness in more severe forms. It is the most common cause of blindness in the elderly. Recent research shows a genetic cause of some forms. While great strides have been made in the treatment of some forms of macular degeneration, it is still largely a disease without a cure. Some studies indicate the value of vitamins and supplements such as anti-oxidants in stabilizing the disease.

   
    Melanoma   This is one of the most common forms of cancer involving the eye. The eye is rich in the pigment “melanin,” and the melanin-containing cells, called melanocytes. Melanoma can arise as a primary tumor in the eye, or as metastatic disease from another part of the body, such as breast cancer. Regular dilated eye examinations can help detect melanoma in the early stage, resulting in a better prognosis.

   
    Optic Nerve Diseases   Besides glaucoma, there are other diseases that result in inflammation or atrophy of the optic nerve. Optic neuritis is one of the most common early signs of MS, or multiple sclerosis. Severe hypertension and certain brain tumors can cause swelling of the optic nerve. Others, such as coloboma and morning glory syndrome are congenital.

   
    Over/under Correction   A result of refractive surgery in which the target correction is missed. Theoretically, an enhancement can be performed if the magnitude of the error is sufficiently large. On the average, 10 percent of laser refractive surgeries will result in an enhancement. Not all enhancements will result in total resolution.

   
    PRK   An acronym for Photorefractive Keratectomy, a surgical method of correcting refractive errors such as nearsightedness, farsightedness, and astigmatism by removing corneal tissue with an excimer laser. PRK was approved in the U.S. in 1997, and precedes the development of LASIK. PRK is still very much in use, although the visual recovery time is longer, and there is more post-operative discomfort. However, surgical complications involving the LASIK flap are avoided.

   
    Pink Eye   See Infection, viral.

   
    Presbyopia   Literally “aging eye,” presbyopia is the progressive loss of near focusing ability as a result of continuous changes in the structure and function of the crystalline lens. While this function begins to decline in late childhood, the effects are not generally appreciated until the fourth decade, when the “arms begin to get too short.” The effects of presbyopia generally peak in the fifth decade. The treatment is reading glasses, bifocals, bifocal contact lenses, or monovision contact lenses.

   
    RK   An acronym for Radial Keratotomy, an older surgical procedure for correcting nearsightedness and astigmatism by making various incisions in the cornea mostly in a radial pie-shaped arrangement. The technique has largely been abandoned in recent years in favor of the safer and more precise excimer laser procedures such as PRK and LASIK.

   
    Recurrent Corneal Erosion – RCE   The chronic condition in which an area of the outermost layer of the cornea suffers from repeated spontaneous and painful erosions, typically on first awakening when the eye is first opened. RCE can occur in an area of previous trauma or abrasion in which the epithelial layer heals imperfectly, forming a relatively loose attachment to its basement membrane. RCE can also occur in epithelial basement membrane dystrophy, in which there is a genetic or acquired flaw in the basement membrane in the absence of trauma. Treatment is generally prophylactic, using light petrolatum ointments, sometimes with sodium chloride added, at night to prevent adhesion of the epithelium to the inside of the eyelid.

   
    Refractive Conditions – Refractive Errors   Also known as myopia, hyperopia, and astigmatism, or nearsightedness, farsightedness, and astigmatism respectively. In the new terminology, they are also called “lower order aberrations.” Myopia results when the image plane of the eye is located in front of or anterior to the retina. Hyperopia results when the image plane is located behind or posterior to the retina. Astigmatism, which may be hyperopic, myopic, or a combination, results when the image does not fall in a single plane, but is spread out, typically in two major planes 90 degrees apart. Myopic eyes are typically longer than average, and hyperopic eyes are shorter than average.

   
    Retinal Disorders   Holes and tears can occur spontaneously and lead to a detachment. Various inflammations infections and inflammations can also affect the retina in addition to tumors and genetic diseases. The importance of routine dilated eye examinations in the detection and treatment of retinal disorders cannot be over-emphasized.

   
    Strabismus   The condition of eye misalignment. Strabismus can either be congenital or acquired. Six muscles, or extraocular muscles, control eye position and movement. Over- or under-action of one or more muscles can result in one or both eyes turning out(exotropia), or turning in(esotropia), or vertically(hypertropia), either intermittently or constantly. The cause of the improper alignment can be central, i.e. in the motor center of the brain controlling eye movement. It can be due to a mechanical restriction within the orbit, or it can be acquired due to damage to one of the cranial nerves controlling the action of one or more extraocular muscles. Esotropia is more common in farsighted children and is often successfully treated with eyeglasses. Some forms of strabismus respond to visual training, while other forms respond to treatment with special lenses called prism. Surgery may also be required.

   
    Styes   A bacterial infection of one of the oil glands in the eyelid, or eyelash follicle. If located superficially on the margin of the eyelid, it is called an external hordeolum If located deep within the meibomian gland within the eyelid, it is called an internal hordeolum. Treatment is usually warm compresses along with a topical or oral antibiotic.

   
    Suppression   Under certain conditions, the vision in one eye can be suppressed by the brain. This most often occurs in strabismus, when the eyes are misaligned. Suppression occurs as a result of the attempt to avoid seeing double. When strabismus occurs early in childhood, or is congenital, suppression almost always results. Strabismus acquired in adulthood is not as easily suppressed.

   
    Tracking Disorders   In reading, the eyes perform a complex series of quick start and stop movements, called saccades. When they reach the end of the sentence, they perform a smooth movement called a return. Efficient readers make fewer saccades and have fewer returns. Inefficient readers make more frequent stops, taking in fewer words, tend to re-read the same line, and often lose their place at the end of the line. Certain vision conditions such as uncorrected refractive error and binocular vision disorders create tracking difficulties. Other kinds of eye movements are important for athletic performance. These are called smooth pursuits. Pursuit movements can also be impaired by vision disorders. Training can enhance reading efficiency and pursuit movements.

   
    Trauma   Common injuries are corneal abrasions and conjunctival lacerations. Blunt trauma can result in hemorrhaging within the eye, as well as retinal tears or detachment. Early assessment is critical.

   
             
             
 

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Copyright 2005 by Greg Gemoules, O.D.
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